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Year : 2014  |  Volume : 28  |  Issue : 1  |  Page : 49-51

Stevens Johnson syndrome due to nevirapine

1 Department of Pharmacology, J. L. N. Medical College, Ajmer, India
2 Department of Chest Diseases and Tuberculosis, Gandhi Medical College, Bhopal, Madhya Pradesh, India
3 Department of Respiratory Medicine, J. L. N. Medical College, Ajmer, India

Correspondence Address:
Ramakant Dixit
A-60, Chandravardai Nagar, Ajmer - 305 001, Rajasthan
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0972-6691.134226

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Adverse drug reactions continue to be among the important cause of morbidity and at times mortality among hospital admissions. The severity of cutaneous adverse drug reaction may vary from mild rashes to severe Stevens Johnson syndrome (SJS). Nevirapine (NVP) is an important component of antiretroviral therapy for patients having acquired immunodeficiency syndrome. It usually cause mild rash in some of these patients. This report describes a case of NVP induced SJS that was reversible on withdrawal of the drug. Possible mechanisms of NVP induced SJS and its clinical implications are also briefly discussed.

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