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ORIGINAL ARTICLE
Year : 2016  |  Volume : 30  |  Issue : 1  |  Page : 12-16

Bronchial challenge testing in mild to moderate asthmatics


Department of Pulmonary Medicine, Grant Government Medical College, Mumbai, Maharashtra, India

Correspondence Address:
Rohit Ratnakar Hegde
Department of Pulmonary Medicine, Grant Government Medical College, Mumbai - 400 008, Maharashtra
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0972-6691.187560

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Background: Bronchial challenge is almost confirmatory test for airway reactivity, a significant test for confirming asthma. Methodology: Already established methodology for the test was used by the direct method using graded concentrations of histamine and using FEV1 as parameter. Results: Fifty mild to moderate asthmatic patients were assessed for airway hyper-responsiveness The youngest was 18 years, the oldest 51 years, the mean age was 34 years. Forty-four percent were males and 56% were females. Bronchial challenge tests were positive in 90% of mild to moderate asthmatic patients. Conclusion: There was a significant linear correlation of PC20 levels with forced expiratory volume in the first second. There was no significant correlation of PC20 levels with serum IgE levels.


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